Assay Detail
Binding
CHEMBL931723
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MTAP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
S-methyl-5'-thioadenosine phosphorylase (CHEMBL4941) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.53 | 10.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405346 | — | — | 1 | 10.05 |
| CHEMBL405371 | — | — | 1 | 8.70 |
| CHEMBL407216 | — | — | 1 | 6.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405346 | — | Ki | = | 0.09 | nM | 10.05 |
| CHEMBL405371 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL407216 | — | Ki | = | 140.0 | nM | 6.85 |