Assay Detail
Binding
CHEMBL932201
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Inhibition of beta amyloid 25-35 fibril formation
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New polyphenols active on beta-amyloid aggregation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.05 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 5.22 |
| CHEMBL403237 | CURCULIGOSIDE B | — | 1 | 5.07 |
| CHEMBL258047 | CURCULIGOSIDE D | — | 1 | 5.02 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 5.00 |
| CHEMBL403236 | OENIN | — | 1 | 5.00 |
| CHEMBL255753 | MALVIDIN | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL165 | RESVERATROL | EC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL403237 | CURCULIGOSIDE B | EC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL258047 | CURCULIGOSIDE D | EC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL140 | CURCUMIN | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL403236 | OENIN | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL255753 | MALVIDIN | EC50 | = | 10000.0 | nM | 5.00 |