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Assay Detail

CHEMBL932343

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of p38
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.
Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ.
Bioorg Med Chem Lett (2008) 18 : 2776 -2780
PubMed 18434142 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.57 4.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL445162 1 4.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL445162 IC50 = 27100.0 nM 4.57