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Assay Detail

CHEMBL932805

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse L1210 cells after 24 hrs in presence of 100 uM spermidine
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Autocuration

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

A comparison of chloroambucil- and xylene-containing polyamines leads to improved ligands for accessing the polyamine transport system.
Kaur N, Delcros JG, Imran J, Khaled A, Chehtane M, Tschammer N, Martin B, Phanstiel O.
J Med Chem (2008) 51 : 1393 -1401
PubMed 18281932 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL558390 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL558390 IC50 = 6960.0 nM 5.16