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Assay Detail

CHEMBL933019

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]DTG from mouse sigma-2 receptor in TRAMP cell membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type TRAMP
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma.
Colabufo NA, Abate C, Contino M, Inglese C, Niso M, Berardi F, Perrone R.
Bioorg Med Chem Lett (2008) 18 : 1990 -1993
PubMed 18276137 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL75286 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL75286 Ki = 0.5 nM 9.30