Assay Detail
Binding
CHEMBL933561
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Streptomyces plicatus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
B-N-acetylhexosaminidase (CHEMBL1075027) ↗| Type | SINGLE PROTEIN |
| Organism | Streptomyces plicatus |
Publication
N-Acetylhexosaminidase inhibitory properties of C-1 homologated GlcNAc- and GalNAc-thiazolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 4.46 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257158 | — | — | 1 | 4.70 |
| CHEMBL253537 | — | — | 1 | 4.68 |
| CHEMBL403756 | — | — | 1 | 4.00 |
| CHEMBL404651 | — | — | 1 | - |
| CHEMBL255693 | — | — | 1 | - |
| CHEMBL403748 | — | — | 1 | - |
| CHEMBL404356 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257158 | — | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL253537 | — | Ki | = | 21000.0 | nM | 4.68 |
| CHEMBL403756 | — | Ki | = | 100000.0 | nM | 4.00 |
| CHEMBL404651 | — | Ki | = | 1600000.0 | nM | - |
| CHEMBL255693 | — | Ki | > | 2000000.0 | nM | - |
| CHEMBL403748 | — | Ki | > | 2000000.0 | nM | - |
| CHEMBL404356 | — | Ki | = | 200000.0 | nM | - |