Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL933563

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human OGA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Protein O-GlcNAcase (CHEMBL5921)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

N-Acetylhexosaminidase inhibitory properties of C-1 homologated GlcNAc- and GalNAc-thiazolines.
Amorelli B, Yang C, Rempel B, Withers SG, Knapp S.
Bioorg Med Chem Lett (2008) 18 : 2944 -2947
PubMed 18406613 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL257158 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL257158 Ki = 70.0 nM 7.16