Assay Detail
Binding
CHEMBL933570
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity at human adenosine A3 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Antagonists of the human adenosine A2A receptor. Part 2: Design and synthesis of 4-arylthieno[3,2-d]pyrimidine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.04 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL260718 | — | — | 1 | 6.34 |
| CHEMBL407307 | — | — | 1 | 6.32 |
| CHEMBL260719 | — | — | 1 | 6.03 |
| CHEMBL402464 | — | — | 1 | 5.75 |
| CHEMBL407650 | — | — | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL260718 | — | Ki | = | 456.0 | nM | 6.34 |
| CHEMBL407307 | — | Ki | = | 476.0 | nM | 6.32 |
| CHEMBL260719 | — | Ki | = | 945.0 | nM | 6.03 |
| CHEMBL402464 | — | Ki | = | 1759.0 | nM | 5.75 |
| CHEMBL407650 | — | Ki | = | 1813.0 | nM | 5.74 |