Assay Detail
Binding
CHEMBL934564
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Inhibition of human DNA polymerase kappa
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.14 | 4.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL260980 | — | — | 1 | 4.22 |
| CHEMBL408995 | TALAROFLAVONE | — | 1 | 4.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL260980 | — | IC50 | = | 59800.0 | nM | 4.22 |
| CHEMBL408995 | TALAROFLAVONE | IC50 | = | 86500.0 | nM | 4.06 |