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Assay Detail

CHEMBL934576

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Binding
Inhibition of JNK2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 9 (CHEMBL4179)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).
Asano Y, Kitamura S, Ohra T, Aso K, Igata H, Tamura T, Kawamoto T, Tanaka T, Sogabe S, Matsumoto S, Yamaguchi M, Kimura H, Itoh F.
Bioorg Med Chem (2008) 16 : 4715 -4732
PubMed 18313304 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.47 7.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259060 1 7.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259060 IC50 = 34.0 nM 7.47