Assay Detail
Binding
CHEMBL936435
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Displacement of [125]Ang4 from endogenous IRAP in CHOK1 cell membrane in presence of EDTA and 1,10-phenanthroline
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cricetulus griseus |
| Cell Type | CHO-K1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Beta-homo-amino acid scan of angiotensin IV.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.86 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408871 | — | — | 1 | 8.24 |
| CHEMBL261120 | ANGIOTENSIN IV | — | 1 | 8.10 |
| CHEMBL261422 | — | — | 1 | 7.70 |
| CHEMBL259019 | — | — | 1 | 7.70 |
| CHEMBL260622 | — | — | 1 | 7.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408871 | — | Ki | = | 5.754 | nM | 8.24 |
| CHEMBL261120 | ANGIOTENSIN IV | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL261422 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL259019 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL260622 | — | Ki | = | 26.3 | nM | 7.58 |