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Assay Detail

CHEMBL936583

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Hsp90
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.
Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL.
Bioorg Med Chem (2008) 16 : 3291 -3301
PubMed 18164205 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL406117 GUSPERIMUS 3.0 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL406117 GUSPERIMUS Kd = 4000.0 nM 5.40