Assay Detail
Functional
CHEMBL936650
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against mouse L1210 cells after 48 hrs by trypan blue staining method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Designing the polyamine pharmacophore: influence of N-substituents on the transport behavior of polyamine conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.77 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL421884 | — | — | 1 | 6.52 |
| CHEMBL258803 | — | — | 1 | 6.40 |
| CHEMBL260931 | — | — | 1 | 6.06 |
| CHEMBL260932 | — | — | 1 | 6.00 |
| CHEMBL429141 | — | — | 1 | 5.92 |
| CHEMBL258876 | — | — | 1 | 5.82 |
| CHEMBL264968 | — | — | 1 | 5.47 |
| CHEMBL419870 | — | — | 1 | 5.12 |
| CHEMBL254003 | — | — | 1 | 4.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL421884 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL258803 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL260931 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL260932 | — | IC50 | = | 1010.0 | nM | 6.00 |
| CHEMBL429141 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL258876 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL264968 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL419870 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL254003 | — | IC50 | = | 22200.0 | nM | 4.65 |