Assay Detail
Binding
CHEMBL936785
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Cdk5/p35
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.01 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL258721 | — | — | 1 | 8.00 |
| CHEMBL286721 | AMINOPURVALANOL | — | 1 | 7.70 |
| CHEMBL23327 | PURVALANOLA | — | 1 | 7.12 |
| CHEMBL14762 | SELICICLIB | 2.0 | 1 | 6.70 |
| CHEMBL280074 | OLOMOUCINE | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL258721 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL286721 | AMINOPURVALANOL | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL23327 | PURVALANOLA | IC50 | = | 75.0 | nM | 7.12 |
| CHEMBL14762 | SELICICLIB | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL280074 | OLOMOUCINE | IC50 | = | 3000.0 | nM | 5.52 |