Assay Detail
Binding
CHEMBL936896
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Inhibition of Cryptococcus neoformans H99 HTA expressed in Escherichia coli BL21(DE3) cells
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cryptococcus neoformans |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Role of homoserine transacetylase as a new target for antifungal agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.04 | 4.04 |
| IC50 | 1 | 5.35 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL271690 | — | — | 2 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL271690 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL271690 | — | Ki | = | 91700.0 | nM | 4.04 |