Assay Detail
Binding
CHEMBL937070
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Inhibition of cdk2/cyclin E
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.32 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286721 | AMINOPURVALANOL | — | 1 | 7.55 |
| CHEMBL80713 | — | — | 1 | 6.30 |
| CHEMBL296586 | KENPAULLONE | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286721 | AMINOPURVALANOL | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL80713 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL296586 | KENPAULLONE | IC50 | = | 7500.0 | nM | 5.12 |