Assay Detail
Binding
CHEMBL937076
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Inhibition of eEF2 kinase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Eukaryotic elongation factor 2 kinase (CHEMBL5026) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.93 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL437612 | — | — | 1 | 6.36 |
| CHEMBL258726 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL437612 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL258726 | — | IC50 | = | 3200.0 | nM | 5.50 |