Assay Detail
Binding
CHEMBL937643
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Inhibition of c-Src
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.78 | 6.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL120077 | — | — | 1 | 6.73 |
| CHEMBL296586 | KENPAULLONE | — | 1 | 4.82 |
| CHEMBL605003 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL120077 | — | IC50 | = | 185.0 | nM | 6.73 |
| CHEMBL296586 | KENPAULLONE | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL605003 | — | IC50 | = | 688000.0 | nM | - |