Assay Detail
Binding
CHEMBL937646
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Inhibition of Cdk1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.07 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL440411 | — | — | 1 | 8.30 |
| CHEMBL337300 | — | — | 1 | 8.30 |
| CHEMBL419931 | — | — | 1 | 7.00 |
| CHEMBL126077 | INDIRUBIN-3-MONOXIME | — | 1 | 6.75 |
| CHEMBL413188 | ISOGRANULATIMIDE | — | 1 | 5.00 |
| CHEMBL120077 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL440411 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL337300 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL419931 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL126077 | INDIRUBIN-3-MONOXIME | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL413188 | ISOGRANULATIMIDE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL120077 | — | IC50 | > | 10000.0 | nM | - |