Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL937652

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition Cdk1/cyclin E
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.60 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259605 1 8.52
CHEMBL1276317 1 6.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259605 IC50 = 3.0 nM 8.52
CHEMBL1276317 IC50 = 210.0 nM 6.68