Assay Detail
Binding
CHEMBL937657
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Cdk5/p25
7
Total Activities
7
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.37 | 7.08 |
| Activity | 1 | - | - |
| Ki | 1 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL409450 | 6BIO | — | 1 | 7.08 |
| CHEMBL75680 | ALOISINE A | — | 1 | 6.70 |
| CHEMBL259389 | QUINOXALINE1 | — | 1 | 6.40 |
| CHEMBL296586 | KENPAULLONE | — | 1 | 6.07 |
| CHEMBL573339 | PI-103 | — | 1 | 5.70 |
| CHEMBL430226 | 6-BROMOINDIRUBIN-3'-ACETOXIME | — | 1 | 5.62 |
| CHEMBL132904 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL409450 | 6BIO | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL75680 | ALOISINE A | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL259389 | QUINOXALINE1 | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL296586 | KENPAULLONE | IC50 | = | 850.0 | nM | 6.07 |
| CHEMBL573339 | PI-103 | Ki | = | 2000.0 | nM | 5.70 |
| CHEMBL430226 | 6-BROMOINDIRUBIN-3'-ACETOXIME | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL132904 | — | Activity | - | — | - |