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Assay Detail

CHEMBL937896

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HSV1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human alphaherpesvirus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human alphaherpesvirus 1 (CHEMBL377)
Type ORGANISM
Organism Human alphaherpesvirus 1

Publication

Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue.
Ying C, Li Y, Leung CH, Robek MD, Cheng YC.
Proc Natl Acad Sci U S A (2007) 104 : 8526 -8531
PubMed 17488817 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.23 6.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL367646 1 6.54
CHEMBL369673 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL367646 IC50 = 290.0 nM 6.54
CHEMBL369673 IC50 = 1200.0 nM 5.92