Assay Detail

CHEMBL937898

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Functional

Antiviral activity against human papilloma virus 11

ChEMBL ↗

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Target

human papillomavirus 11 (CHEMBL613717) ↗

Open DB target context

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human papillomavirus 11 (CHEMBL613717) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target human papillomavirus 11

CHEMBL613717

Anchored from Assay target.

Protein identity human papillomavirus 11

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	human papillomavirus 11
Confidence	1 — Organism
Curated By	Autocuration

Target

human papillomavirus 11 (CHEMBL613717) ↗

Type	ORGANISM
Organism	human papillomavirus 11

Publication

Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue.

Ying C, Li Y, Leung CH, Robek MD, Cheng YC.
Proc Natl Acad Sci U S A (2007) 104 : 8526 -8531
PubMed 17488817 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	5.97	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL367646	—	—	1	6.70
CHEMBL369673	—	—	1	5.24

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL367646	—	IC50	=	200.0	nM	6.70
CHEMBL369673	—	IC50	=	5800.0	nM	5.24