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Assay Detail

CHEMBL937901

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Escherichia coli DXR by spectrophotometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis.
Henriksson LM, Unge T, Carlsson J, Aqvist J, Mowbray SL, Jones TA.
J Biol Chem (2007) 282 : 19905 -19916
PubMed 17491006 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL203125 FOSMIDOMYCIN 3.0 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL203125 FOSMIDOMYCIN IC50 = 30.0 nM 7.52