Assay Detail
Functional
CHEMBL938341
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Antimalarial activity against chloroquine-resistant Plasmodium falciparum FcB1R after 72 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 7.27 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92547 | — | — | 1 | 7.77 |
| CHEMBL328742 | — | — | 1 | 7.72 |
| CHEMBL264512 | — | — | 1 | 7.26 |
| CHEMBL329647 | — | — | 1 | 7.24 |
| CHEMBL56640 | — | — | 1 | 7.21 |
| CHEMBL90969 | — | — | 1 | 7.20 |
| CHEMBL258645 | — | — | 1 | 6.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92547 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL328742 | — | EC50 | = | 19.0 | nM | 7.72 |
| CHEMBL264512 | — | EC50 | = | 55.0 | nM | 7.26 |
| CHEMBL329647 | — | EC50 | = | 57.0 | nM | 7.24 |
| CHEMBL56640 | — | EC50 | = | 61.0 | nM | 7.21 |
| CHEMBL90969 | — | EC50 | = | 63.0 | nM | 7.20 |
| CHEMBL258645 | — | EC50 | = | 330.0 | nM | 6.48 |