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Assay Detail

CHEMBL939211

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of p38-beta MAP kinase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 11 (CHEMBL3961)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.18 7.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL97162 1 7.36
CHEMBL278041 SB-202190 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL97162 IC50 = 44.0 nM 7.36
CHEMBL278041 SB-202190 IC50 = 100.0 nM 7.00