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Assay Detail

CHEMBL939343

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Binding
Inhibition of p34cdc2/cyclin B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL23327 PURVALANOLA 1 8.40
CHEMBL407391 DIMETHYLADENINE 1 -
CHEMBL35820 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL23327 PURVALANOLA IC50 = 4.0 nM 8.40
CHEMBL407391 DIMETHYLADENINE IC50 = 300000.0 nM -
CHEMBL35820 IC50 = 300000.0 nM -