Assay Detail

CHEMBL939349

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of tyrosine kinase

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	8.52	8.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL416056	—	—	1	8.52
CHEMBL258765	FASCAPLYSIN CHLORIDE	—	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL416056	—	IC50	=	3.0	nM	8.52
CHEMBL258765	FASCAPLYSIN CHLORIDE	IC50	>	10000.0	nM	-