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Assay Detail

CHEMBL939356

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Binding
Binding affinity to ERK2
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 1 (CHEMBL4040)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.51 6.51
Kd 1 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259551 1 6.51
CHEMBL262615 HIAZOLIDINEDIONE1 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259551 Ki = 310.0 nM 6.51
CHEMBL262615 HIAZOLIDINEDIONE1 Kd = 5000.0 nM 5.30