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Assay Detail

CHEMBL939379

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Binding
Binding affinity at PKA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S.
Proc Natl Acad Sci U S A (2007) 104 : 20523 -20528
PubMed 18077363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.92 7.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL104264 1 7.32
CHEMBL406821 1 6.20
CHEMBL143054 1 5.64
CHEMBL429298 1 4.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL104264 Ki = 48.0 nM 7.32
CHEMBL406821 Ki = 630.0 nM 6.20
CHEMBL143054 Ki = 2300.0 nM 5.64
CHEMBL429298 Ki = 32000.0 nM 4.50