Assay Detail
Binding
CHEMBL939647
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MEK1 in mouse C2C12 by ERK2 phosphorylation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Dual specificity mitogen-activated protein kinase kinase 1 (CHEMBL5860) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Reversine increases the plasticity of lineage-committed mammalian cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.10 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188343 | REVERSINE | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188343 | REVERSINE | IC50 | = | 8.0 | nM | 8.10 |