Assay Detail
Binding
CHEMBL939873
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to dopamine transporter
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Sodium-dependent dopamine transporter (CHEMBL238) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Antagonists of the calcium receptor I. Amino alcohol-based parathyroid hormone secretagogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.28 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2112075 | — | — | 1 | 6.70 |
| CHEMBL504479 | — | — | 1 | 6.52 |
| CHEMBL523475 | — | — | 1 | 5.96 |
| CHEMBL486278 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2112075 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL504479 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL523475 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL486278 | — | IC50 | = | 1200.0 | nM | 5.92 |