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Assay Detail

CHEMBL940154

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Binding
Inhibition of [3H]L-aspartate uptake at Pyrococcus horikoshii sodium-coupled aspartate transporter after 3 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pyrococcus horikoshii
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Boudker O, Ryan RM, Yernool D, Shimamoto K, Gouaux E.
Nature (2007) 445 : 387 -393
PubMed 17230192 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.48 5.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL475341 1 5.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL475341 IC50 = 3300.0 nM 5.48