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Assay Detail

CHEMBL940819

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Functional
DPPH radical scavenging activity after 30 mins
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Synthetic tyrosyl gallate derivatives as potent melanin formation inhibitors.
Lee CW, Son EM, Kim HS, Xu P, Batmunkh T, Lee BJ, Koo KA.
Bioorg Med Chem Lett (2007) 17 : 5462 -5464
PubMed 17693086 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.04 5.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL147069 1 5.12
CHEMBL246622 1 5.11
CHEMBL399354 1 5.08
CHEMBL47 ALPHA-TOCOPHEROL 1 5.00
CHEMBL196 ASCORBIC ACID 4.0 1 4.87

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL147069 IC50 = 7520.0 nM 5.12
CHEMBL246622 IC50 = 7780.0 nM 5.11
CHEMBL399354 IC50 = 8310.0 nM 5.08
CHEMBL47 ALPHA-TOCOPHEROL IC50 = 9890.0 nM 5.00
CHEMBL196 ASCORBIC ACID IC50 = 13600.0 nM 4.87