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Assay Detail

CHEMBL941185

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]CP-55-940 from human recombinant CB1 receptor expressed in COS cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type COS
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 1 (CHEMBL218)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity.
Balas L, Durand T, Saha S, Johnson I, Mukhopadhyay S.
J Med Chem (2009) 52 : 1005 -1017
PubMed 19161308 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.36 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL15848 ANANDAMIDE 1 7.16
CHEMBL513597 1 5.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL15848 ANANDAMIDE Ki = 70.0 nM 7.16
CHEMBL513597 Ki = 2800.0 nM 5.55