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Assay Detail

CHEMBL941867

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse L1210 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Autocuration

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis, anticancer, and cytotoxic activities of some mononuclear Ru(II) compounds.
Karki SS, Thota S, Darj SY, Balzarini J, De Clercq E.
Bioorg Med Chem (2007) 15 : 6632 -6641
PubMed 17765549 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 4.13 4.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL394260 1 4.17
CHEMBL239452 1 4.08
CHEMBL333137 1 -
CHEMBL393467 1 -
CHEMBL391982 1 -
CHEMBL398206 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL394260 IC50 = 68000.0 nM 4.17
CHEMBL239452 IC50 = 84000.0 nM 4.08
CHEMBL333137 IC50 = 382000.0 nM -
CHEMBL393467 IC50 = 242000.0 nM -
CHEMBL391982 IC50 = 284000.0 nM -
CHEMBL398206 IC50 = 232000.0 nM -