Assay Detail
Binding
CHEMBL942401
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of p60c-src expressed in chick embryo fibroblast
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.46 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL752 | ADENOSINE PHOSPHATE | 4.0 | 1 | 7.00 |
| CHEMBL490984 | — | — | 1 | 5.05 |
| CHEMBL339385 | DIADENOSINE TETRAPHOSPHATE | — | 1 | 4.34 |
| CHEMBL448348 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL752 | ADENOSINE PHOSPHATE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL490984 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL339385 | DIADENOSINE TETRAPHOSPHATE | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL448348 | — | IC50 | > | 100000.0 | nM | - |