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Assay Detail

CHEMBL943121

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of Leishmania major promastigotes assessed as [3H]thymidine incorporation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania major
Confidence 1 — Organism
Curated By Intermediate

Target

Leishmania major (CHEMBL612879)
Type ORGANISM
Organism Leishmania major

Publication

A review of anti-infective and anti-inflammatory chalcones.
Nowakowska Z.
Eur J Med Chem (2007) 42 : 125 -137
PubMed 17112640 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL139702 LICOAGROCHACONE A 1 5.40
CHEMBL253672 1 5.40
CHEMBL434066 1 5.40
CHEMBL144626 1 5.40
CHEMBL143265 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL139702 LICOAGROCHACONE A IC50 = 4000.0 nM 5.40
CHEMBL253672 IC50 = 4000.0 nM 5.40
CHEMBL434066 IC50 = 4000.0 nM 5.40
CHEMBL144626 IC50 = 4000.0 nM 5.40
CHEMBL143265 IC50 = 4000.0 nM 5.40