Assay Detail
Functional
CHEMBL943128
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 by [3H]hypoxanthine incorporation
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
A review of anti-infective and anti-inflammatory chalcones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.02 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL139479 | — | — | 1 | 5.19 |
| CHEMBL137883 | — | — | 1 | 5.19 |
| CHEMBL279386 | — | — | 1 | 5.19 |
| CHEMBL139086 | — | — | 1 | 5.19 |
| CHEMBL140130 | — | — | 1 | 5.19 |
| CHEMBL136132 | — | — | 1 | 5.19 |
| CHEMBL139679 | — | — | 1 | 4.91 |
| CHEMBL137913 | — | — | 1 | 4.70 |
| CHEMBL7721 | — | — | 1 | 4.70 |
| CHEMBL141749 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL139479 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL137883 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL279386 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL139086 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL140130 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL136132 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL139679 | — | IC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL137913 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL7721 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL141749 | — | IC50 | = | 20000.0 | nM | 4.70 |