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Assay Detail

CHEMBL943130

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

A review of anti-infective and anti-inflammatory chalcones.
Nowakowska Z.
Eur J Med Chem (2007) 42 : 125 -137
PubMed 17112640 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.99 4.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL253677 5'-PRENYLBUTEIN 1 4.99
CHEMBL144686 HOMOBUTEIN 1 4.99
CHEMBL139702 LICOAGROCHACONE A 1 4.99

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL253677 5'-PRENYLBUTEIN IC50 = 10300.0 nM 4.99
CHEMBL144686 HOMOBUTEIN IC50 = 10300.0 nM 4.99
CHEMBL139702 LICOAGROCHACONE A IC50 = 10300.0 nM 4.99