Assay Detail
Functional
CHEMBL943602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
DNA damaging activity against RAD52 transformed Saccharomyces cerevisiae in glucose minimal medium after 41 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Saccharomyces cerevisiae |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
DNA-damaging agents from Crypteronia paniculata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.53 | 5.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL517610 | NYSSOSIDE | — | 1 | 5.95 |
| CHEMBL492172 | — | — | 1 | 5.51 |
| CHEMBL240528 | AFZELIN | — | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL517610 | NYSSOSIDE | IC50 | = | 1120.0 | nM | 5.95 |
| CHEMBL492172 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL240528 | AFZELIN | IC50 | = | 7400.0 | nM | 5.13 |