Assay Detail
Functional
CHEMBL943604
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DNA damaging activity against YCp50 transformed Saccharomyces cerevisiae in glucose minimal medium after 41 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Saccharomyces cerevisiae |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
DNA-damaging agents from Crypteronia paniculata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.38 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL517610 | NYSSOSIDE | — | 1 | 6.47 |
| CHEMBL240528 | AFZELIN | — | 1 | 5.03 |
| CHEMBL492172 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL517610 | NYSSOSIDE | IC50 | = | 341.0 | nM | 6.47 |
| CHEMBL240528 | AFZELIN | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL492172 | — | IC50 | = | 23100.0 | nM | 4.64 |