Assay Detail
Binding
CHEMBL943941
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Inhibition of Methanobacterium thermoautotrophicum ODCase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Methanothermobacter thermautotrophicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.56 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463623 | — | — | 1 | 6.72 |
| CHEMBL514137 | — | — | 1 | 6.08 |
| CHEMBL463480 | 6-AZA-URIDINE MONOPHOSPHATE | — | 1 | 4.91 |
| CHEMBL512577 | — | — | 1 | 4.54 |
| CHEMBL472783 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463623 | — | Ki | = | 190.0 | nM | 6.72 |
| CHEMBL514137 | — | Ki | = | 840.0 | nM | 6.08 |
| CHEMBL463480 | 6-AZA-URIDINE MONOPHOSPHATE | Ki | = | 12400.0 | nM | 4.91 |
| CHEMBL512577 | — | Ki | = | 29000.0 | nM | 4.54 |
| CHEMBL472783 | — | Ki | = | 134000.0 | nM | - |