Assay Detail
Binding
CHEMBL944039
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Inhibition of MMP14
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
A novel series of highly selective inhibitors of MMP-3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.88 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL398641 | — | — | 1 | 5.77 |
| CHEMBL251917 | — | — | 1 | 4.70 |
| CHEMBL250266 | — | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL398641 | — | IC50 | = | 1710.0 | nM | 5.77 |
| CHEMBL251917 | — | IC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL250266 | — | IC50 | = | 66900.0 | nM | 4.17 |