Assay Detail
Functional
CHEMBL944128
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Antiproliferative activity against human SF268 cells by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SF-268 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Uncovering biosynthetic potential of plant-associated fungi: effect of culture conditions on metabolite production by Paraphaeosphaeria quadriseptata and Chaetomium chiversii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.58 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.40 |
| CHEMBL404204 | MONOCILLIN III | — | 1 | 6.52 |
| CHEMBL252324 | — | — | 1 | 6.26 |
| CHEMBL215853 | MONOCILLIN I | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL404204 | MONOCILLIN III | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL252324 | — | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL215853 | MONOCILLIN I | IC50 | = | 720.0 | nM | 6.14 |