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Assay Detail

CHEMBL944159

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity at 5HT7 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

5-hydroxytryptamine receptor 7 (CHEMBL3155)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advances in development of dopaminergic aporphinoids.
Zhang A, Zhang Y, Branfman AR, Baldessarini RJ, Neumeyer JL.
J Med Chem (2007) 50 : 171 -181
PubMed 17228858 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.11 8.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL281924 1 8.96
CHEMBL253318 1 7.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL281924 Ki = 1.1 nM 8.96
CHEMBL253318 Ki = 55.0 nM 7.26