Assay Detail
Binding
CHEMBL944649
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of (-)-[3H]devapamil from L-type calcium channel in rabbit skeletal muscle cells
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anthracene based compounds as new L-type Ca2+ channel blockers: design, synthesis, and full biological profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.25 | 5.25 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL475745 | — | — | 1 | 5.25 |
| CHEMBL6966 | VERAPAMIL | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL475745 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL6966 | VERAPAMIL | Inhibition | = | 100.0 | % | - |