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Assay Detail

CHEMBL944973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Plasmodium falciparum PFT
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Plasmodium falciparum
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

2-Oxotetrahydroquinoline-based antimalarials with high potency and metabolic stability.
Bulbule VJ, Rivas K, Verlinde CL, Van Voorhis WC, Gelb MH.
J Med Chem (2008) 51 : 384 -387
PubMed 18198825 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL232104 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL232104 IC50 = 0.5 nM 9.30