Assay Detail
Functional
CHEMBL945827
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Growth inhibition of HUVEC cells by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hybrid angiogenesis inhibitors: synthesis and biological evaluation of bifunctional compounds based on 1-deoxynojirimycin and aryl-1,2,3-triazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | 5.70 |
| CHEMBL254339 | — | — | 1 | 5.70 |
| CHEMBL254145 | — | — | 1 | 5.70 |
| CHEMBL401628 | — | — | 1 | 5.70 |
| CHEMBL254117 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL254339 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL254145 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL401628 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL254117 | — | IC50 | = | 2000.0 | nM | 5.70 |