Assay Detail
Binding
CHEMBL945897
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to 5HT3 receptor
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Multi-target-directed ligands to combat neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.87 | 9.48 |
| IC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15056 | — | — | 1 | 9.48 |
| CHEMBL195241 | — | — | 1 | 8.25 |
| CHEMBL220808 | SARIZOTAN | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15056 | — | Ki | = | 0.33 | nM | 9.48 |
| CHEMBL195241 | — | Ki | = | 5.6 | nM | 8.25 |
| CHEMBL220808 | SARIZOTAN | IC50 | < | 6.0 | nM | - |